منابع مشابه
Targeted antimicrobial therapy in the microbiome era
Even though the oral microbiome is one of the most complex sites on the body it is an excellent model for narrow-spectrum antimicrobial therapy. Current research indicates that disruption of the microbiome leads to a dysbiotic environment allowing for the overgrowth of pathogenic species and the onset of oral diseases. The gram-negative colonizer, Porphyromonas gingivalis has long been consider...
متن کاملThe gut microbiome, kidney disease, and targeted interventions.
The human gut harbors >100 trillion microbial cells, which influence the nutrition, metabolism, physiology, and immune function of the host. Here, we review the quantitative and qualitative changes in gut microbiota of patients with CKD that lead to disturbance of this symbiotic relationship, how this may contribute to the progression of CKD, and targeted interventions to re-establish symbiosis...
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Denial of service attacks can be catastrophic in wireless sensor networks. Typical denial of service attacks consist of either communications jamming or resource depletion through forcing continuous stimuli and communication between motes on the network. Localization is another interesting challenge in the world of sensor networks. Many applications utilizing sensor networks require that the an...
متن کاملHuman Microbiome
Humans are almost identical in their genetic pattern, but the slight differences in our DNA lead to remarkable phenotypic variation among the human population. There are a variety of microbial communities and their genes (microbiomes) in the human body that play an essential role in human health and disease. The microbes inhabiting our bodies is quite a bit more variable, with only a third of i...
متن کاملTargeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans.
OBJECTIVE Gut microbiota represent a potential novel target for future prediabetes and type 2 diabetes therapies. In that respect, niacin has been shown to beneficially affect the host-microbiome interaction in rodent models. RESEARCH DESIGN AND METHODS We characterized more than 500 human subjects with different metabolic phenotypes regarding their niacin (nicotinic acid [NA] and nicotinamid...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2020
ISSN: 1740-1526,1740-1534
DOI: 10.1038/s41579-020-0397-9